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Interleukin 6 (IL6), also referred to as B-cell stimulatory factor-2 (BSF-2) and interferon beta-2, is a cytokine involved in a wide variety of biological functions. [20] It plays an essential role in the final differentiation of B cells into immunoglobulin-secreting cells, as well as inducing myeloma/plasmacytoma growth, nerve cell differentiation, and, in hepatocytes, acute-phase reactants. [20] [21] Hillard, James (October 2008). "The Illinois Constitution: A Primer". Illinois Bar Journal. 96 (10): 494. Archived from the original on November 2, 2019 . Retrieved November 2, 2019. Native Americans:American Indian Tribes of Illinois". Museum.state.il.us. October 2, 2002. Archived from the original on March 22, 2016 . Retrieved February 27, 2016.

a b c d Milburn MV, Hassell AM, Lambert MH, Jordan SR, Proudfoot AE, Graber P, Wells TN (May 1993). "A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5". Nature. 363 (6425): 172–6. Bibcode: 1993Natur.363..172M. doi: 10.1038/363172a0. PMID 8483502. S2CID 4254991. A significant number of adherents of other Abrahamic faiths can be found in Illinois. Largely concentrated in the Chicago metropolitan area, followers of the Muslim, Baháʼí, and Jewish religions all call the state home. [113] Muslims constituted the largest non-Christian group, with 359,264 adherents. [114] Illinois has the largest concentration of Muslims by state in the country, with 2,800 Muslims per 100,000 citizens. [115] Microsoft Windows user's computer can type an "è" by pressing Alt+ 0 2 3 2 or Alt+ 1 3 8 on the numeric pad of the keyboard. "È" can be typed by pressing Alt+ 0 2 0 0 or Alt+ 2 1 2.

Arena A, Merendino RA, Bonina L, Iannello D, Stassi G, Mastroeni P (Apr 2000). "Role of IL-15 on monocytic resistance to human herpesvirus 6 infection". The New Microbiologica. 23 (2): 105–12. PMID 10872679. Modi WS, Dean M, Seuanez HN, Mukaida N, Matsushima K, O'Brien SJ (1990). "Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8) resides in a gene cluster along with several other members of the platelet factor 4 gene superfamily". Hum. Genet. 84 (2): 185–7. doi: 10.1007/BF00208938. PMID 1967588. S2CID 2217894. Adlai Stevenson II (1900–1965), son of Lewis, served as Governor of Illinois and as the U.S. Ambassador to the United Nations; he was also the Democratic party's presidential nominee in 1952 and 1956, losing both elections to Dwight Eisenhower. Kotowicz K, Callard RE, Friedrich K, Matthews DJ, Klein N (Dec 1996). "Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor". Int Immunol. 8 (12): 1915–25. doi: 10.1093/intimm/8.12.1915. PMID 8982776.

ILCS 460/20) (from Ch. 1, par. 2901‑20) State Designations Act". Illinois Compiled Statutes. Springfield, Illinois: Illinois General Assembly. September 4, 1991. Archived from the original on March 5, 2009 . Retrieved April 10, 2009. Sec. 20. Official language. The official language of the State of Illinois is English. The state features 13 athletic programs that compete in NCAA DivisionI, the highest level of U.S. college sports. a b c d e Horsley, A. Doyne (1986). Illinois: A Geography. Boulder: Westview Press. ISBN 978-0-86531-522-8.ComEd and Electricity Related Messages for Economic Development" (PDF). Archived from the original (PDF) on July 8, 2011 . Retrieved February 7, 2011. After it was established in 1833, Chicago gained prominence as a Great Lakes port, and then as an Illinois and Michigan Canal port after 1848, and as a rail hub soon afterward. By 1857, Chicago was Illinois's largest city. [30] With the tremendous growth of mines and factories in the state in the 19th century, Illinois was the ground for the formation of labor unions in the United States. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice. [2] History and name [ edit ] Stimulates growth and differentiation of B cells ( IgE), inhibits TH1-cells and the production of macrophage inflammatory cytokines (e.g. IL-1, IL-6), ↓ IL-8, IL-10, IL-12

Schulte, Sarah (April 28, 2021). "2020 census results: Illinois loses population, but not from where you'd think". ABC7 Chicago. Archived from the original on May 12, 2021 . Retrieved May 12, 2021. Three families from Illinois have played particularly prominent roles in the Democratic Party, gaining both statewide and national fame. The winter of 1830–1831 is called the "Winter of the Deep Snow"; [37] a sudden, deep snowfall blanketed the state, making travel impossible for the rest of the winter, and many travelers perished. Several severe winters followed, including the "Winter of the Sudden Freeze". On December 20, 1836, a fast-moving cold front passed through, freezing puddles in minutes and killing many travelers who could not reach shelter. The adverse weather resulted in crop failures in the northern part of the state. The southern part of the state shipped food north, and this may have contributed to its name, " Little Egypt", after the Biblical story of Joseph in Egypt supplying grain to his brothers. [38]Snow, Dean (2010). Archaeology of Native North Americas. Upper Saddle River, NJ: Prentice Hall. pp.201–203. The Chicago metropolitan area also hosts two zoos: The Brookfield Zoo, located about ten miles west of the city center in suburban Brookfield, contains more than 2,300 animals and covers 216 acres (87ha). The Lincoln Park Zoo is located in Lincoln Park on Chicago's North Side, approximately 3 miles (4.8km) north of the Loop. The zoo accounts for more than 35 acres (14ha) of the park. Ready for Research" (PDF). Archived from the original (PDF) on October 6, 2013 . Retrieved September 12, 2013. Tareen, Sophia (August 28, 2017). "Governor Signs Law Limiting Illinois Police on Immigration". ABC News (from the Associated Press). Archived from the original on September 10, 2017 . Retrieved September 3, 2019. Data" (PDF). Centers for Disease Control and Prevention. Archived (PDF) from the original on November 28, 2019 . Retrieved December 2, 2019.

The Association of Religion Data Archives | State Membership Report". www.thearda.com. Archived from the original on November 12, 2013 . Retrieved November 12, 2013. a b "Illinois Selected Social Characteristics in the United States: 2007". 2007 American Community Survey 1-Year Estimates. U.S. Census Bureau. 2007. Archived from the original on February 11, 2020 . Retrieved April 9, 2009. Illinois Town Gives Up on Futurgen". Permianbasin360.com. August 12, 2010. Archived from the original on March 9, 2012 . Retrieved April 29, 2012. Ryan, Camille (August 2013). "Language Use in the United States: American Community Survey Reports" (PDF). Census.gov. United States Census Bureau. Archived from the original (PDF) on February 5, 2016 . Retrieved March 30, 2014. a b c Abbas AK, Lichtman AH, Pillai S (2012). Cellular and molecular immunology (7thed.). Philadelphia: Elsevier/Saunders. ISBN 978-1437715286.Illinois had a prominent role in the emergence of the nuclear age. In 1942, as part of the Manhattan Project, the University of Chicago conducted the first sustained nuclear chain reaction. In 1957, Argonne National Laboratory, near Chicago, activated the first experimental nuclear power generating system in the United States. By 1960, the first privately financed nuclear plant in the United States, Dresden 1, was dedicated near Morris. In 1967, Fermilab, a national nuclear research facility near Batavia, opened a particle accelerator, which was the world's largest for over 40 years. With eleven plants currently operating, Illinois leads all states in the amount of electricity generated from nuclear power. [48] [49]